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1

Cloning of bovine GAP and its interaction with oncogenic ras p21

Vogel, Ursula S., Dixon, Richard A. F., Schaber, Michael D., Diehl, Ronald E., Marshall, Mark S., Scolnick, Edward M., Sigal, Irving S., Gibbs, Jackson B.

Journal:

Year:

1988

File:

PDF, 563 KB

1988

2

[Part 1: Biological Sciences] || Thiol-β -lactamase: Replacement of the Active-Site Serine of RTEM β -lactamase by a Cysteine Residue

Irving S. Sigal, Betty G. Harwood and Rene Arentzen

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.19 MB

english, 1982

3

Design and synthesis of HIV protease inhibitors. Variations of the carboxyterminus of the HIV protease inhibitor L-682,679

DeSolms, S. Jane, Giuliani, Elizabeth A., Guare, James P., Vacca, Joseph P., Sanders, William M., Graham, Samuel L., Wiggins, J. Mark, Darke, Paul L., Sigal, Irving S.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 772 KB

english, 1991

4

Ras interaction with the GTPase-activating protein (GAP)

Michael D. Schaber, Victor M. Garsky, Douglas Boylan, Wendy S. Hill, Edward M. Scolnick, Mark S. Marshall, Irving S. Sigal, Jackson B. Gibbs

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 946 KB

english, 1989

5

Genetic analysis of the molecular basis for β-adrenergic receptor subtype specificity

Richard A. F. Dixon, Wendy S. Hill, Mari R. Candelore, Elaine Rands, Ronald E. Diehl, Mark S. Marshall, Irving S. Sigal, Catherine D. Strader

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 771 KB

english, 1989

6

Yeast and mammalian ras proteins have conserved biochemical properties

Temeles, Gretchen L., Gibbs, Jackson B., D'Alonzo, Jill S., Sigal, Irving S., Scolnick, Edward M.

Journal:

Year:

1985

File:

PDF, 483 KB

1985

7

Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core

Dixon, Richard A. F., Sigal, Irving S., Rands, Elaine, Register, R. Bruce, Candelore, Mari Rios, Blake, Allan D., Strader, Catherine D.

Journal:

Year:

1987

File:

PDF, 564 KB

1987

8

A structure and some function

Sigal, Irving S.

Journal:

Year:

1988

File:

PDF, 267 KB

1988

9

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Navia, Manuel A., Fitzgerald, Paula M. D., McKeever, Brian M., Leu, Chih-Tai, Heimbach, Jill C., Herber, Wayne K., Sigal, Irving S., Darke, Paul L., Springer, James P.

Journal:

Year:

1989

File:

PDF, 668 KB

1989

10

Affinity purification of the HIV-1 protease

Jill C. Heimbach, Victor M. Garsky, Stuart R. Michelson, Richard A.F. Dixon, Irving S. Sigal, Paul L. Darke

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 539 KB

english, 1989

11

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Paul L. Darke, Ruth F. Nutt, Stephen F. Brady, Victor M. Garsky, Terrence M. Ciccarone, Chih-Tai Leu, Patricia K. Lumma, Roger M. Freidinger, Daniel F. Veber, Irving S. Sigal

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 348 KB

english, 1988

12

Biochemical properties of normal and oncogenic ras p21

Gibbs, Jackson B., Sigal, Irving S., Scolnick, Edward M.

Journal:

Trends in Biochemical Sciences

Year:

1985

Language:

english

File:

PDF, 473 KB

english, 1985

13

The carboxyl terminus of the hamster β-adrenergic receptor expressed in mouse L cells is not required for receptor sequestration

Strader, Catherine D., Sigal, Irving S., Blake, Allan D., Cheung, Anne H., Register, R.Bruce, Rands, Elaine, Zemcik, Barbara A., Candelore, Mari Rios, Dixon, Richard A.F.

Journal:

Year:

1987

Language:

english

File:

PDF, 2.45 MB

english, 1987

14

[Part 1: Biological Sciences] || Intrinsic GTPase Activity Distinguishes Normal and Oncogenic ras p21 Molecules

Jackson B. Gibbs, Irving S. Sigal, Martin Poe and Edward M. Scolnick

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.42 MB

english, 1984

15

Mutant ras-Encoded Proteins with Altered Nucleotide Binding Exert Dominant Biological Effects

Irving S. Sigal, Jackson B. Gibbs, Jill S. D'Alonzo, Gretchen L. Temeles, Bohdan S. Wolanski, Susan H. Socher and Edward M. Scolnick

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.11 MB

english, 1986

16

Identification of Effector Residues and a Neutralizing Epitope of Ha-ras-Encoded p21

Irving S. Sigal, Jackson B. Gibbs, Jill S. D'Alonzo and Edward M. Scolnick

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 999 KB

english, 1986

17

cDNA for the Human β2-Adrenergic Receptor: A Protein with Multiple Membrane-Spanning Domains and Encoded by a Gene Whose Chromosomal Location is Shared with that of the Receptor for Platelet-Derived Growth Factor

Brian K. Kobilka, Richard A. F. Dixon, Thomas Frielle, Henrik G. Dohlman, Mark A. Bolanowski, Irving S. Sigal, Teresa L. Yang-Feng, Uta Francke, Marc G. Caron and Robert J. Lefkowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.01 MB

english, 1987

18

Identification of Residues Required for Ligand Binding to the β -adrenergic Receptor

Catherine D. Strader, Irving S. Sigal, R. Bruce Register, Mari Rios Candelore, Elaine Rands and Richard A. F. Dixon

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 782 KB

english, 1987

19

Active Human Immunodeficiency Virus Protease is Required for Viral Infectivity

Nancy E. Kohl, Emilio A. Emini, William A. Schleif, Lenora J. Davis, Jill C. Heimbach, Richard A. F. Dixon, Edward M. Scolnick and Irving S. Sigal

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 990 KB

english, 1988

20

Chemical Synthesis and Enzymatic Activity of a 99-Residue Peptide with a Sequence Proposed for the Human Immunodeficiency Virus Protease

Ruth F. Nutt, Stephen F. Brady, Paul L. Darke, Terrence M. Ciccarone, C. Dylion Colton, Elka M. Nutt, John A. Rodkey, Carl D. Bennett, Lloyd H. Waxman, Irving S. Sigal, Paul S. Anderson and Daniel F.

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.12 MB

english, 1988

21

Purification of Ras GTPase Activating Protein from Bovine Brain

Jackson B. Gibbs, Michael D. Schaber, W. Jeffrey Allard, Irving S. Sigal and Edward M. Scolnick

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 874 KB

english, 1988

22

Xenopus Oocyte Germinal-Vesicle Breakdown Induced by [Val12]Ras is Inhibited by a Cytosol-Localized Ras Mutant

Jackson B. Gibbs, Michael D. Schaber, Timothy L. Schofield, Edward M. Scolnick and Irving S. Sigal

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 851 KB

english, 1989

23

Disproportionation among aryloxyphosphoranes

Sigal, Irving S., Westheimer, F. H.

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 698 KB

english, 1979

24

Additions and Corrections - Disproportionation among Aryloxyphosphoranes.

Sigal, Irving, Westheimer, F.

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 145 KB

english, 1980

25

A phosphorus analog of .alpha.-pyrone and evidence for monomeric mesitylmetaphosphonate

Sigal, Irving, Loew, Leslie

Journal:

Journal of the American Chemical Society

Year:

1978

Language:

english

File:

PDF, 685 KB

english, 1978

26

Correction. Ionization of Aryloxyphosphoranes in Acetonitrile: Rates and Equilibria

Sigal, Irving, Westheimer, F

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 119 KB

english, 1981

27

Ionization of aryloxyphosphoranes in acetonitrile: rates and equilibriums

Sigal, Irving S., Westheimer, F. H.

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 641 KB

english, 1979

28

Sequence of the gene encoding the human M1 muscarinic acetylcholine receptor

Allard, W.Jeffrey, Sigal, Irving S., Dixon, Richard A.F.

Journal:

Nucleic Acids Research

Year:

1987

Language:

english

File:

PDF, 74 KB

english, 1987

29

Mapping the Functional Domains of the β-adrenergic Receptor

Strader, Catherine D., Sigal, Irving S., Dixon, Richard A. F.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1989

Language:

english

File:

PDF, 631 KB

english, 1989